Macromolecular complexes form the machinery responsible for most biological
processes and are relevant to the understanding of many diseases such as
cancer and metabolic disorders. To this end, the Computational Center for
Biomolecular Complexes (CCBC), a virtual center focused on the computational
aspects of specimen selection, biochemical purification, structural
characterization and functional mechanism of biomolecular complexes, has
been established, bringing together investigators from diverse disciplines
including crystallography, electron cryomicroscopy,
bioinformatics, cell biology, biochemistry, genetics, computational science,
computer science and software engineering.
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