Three-dimensional Visualization of mRNA Release from Actively-Transcribing Rotavirus Particles

Nat Struct Biol. 1997 4:118-121.

Jeffrey A. Lawton***, Mary K. Estes**, and B. V. Venkataram Prasad*

* Verna and Marrs McLean Deartment of Biochemistry, and the W.M. Keck Center for Computational Biology; ** Division of Molecular Virology; *** Program in Cell and Molecular Biology,
Baylor College of Medicine, One Baylor Plaza, Houston, Texas 77030, USA


The three-dimensional structure of actively-transcribing rotavirus particles reveals that the nascent mRNA transcripts generated within the core of the virion by endogenous transcriptase complexes are translocated through the intact capsid via a system of channels at the icosahedral 5-fold axes.

Copyright 1996

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